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In this Huberman Lab Essentials episode, I explore how the nervous system impacts fat loss and how certain behaviors and supplements can accelerate fat burning.
I explain how non-exercise movements like fidgeting and shivering trigger adrenaline to boost fat metabolism. I also examine the impact of exercise intensity and fasted workouts on fat burning, and how supplements such as caffeine, GLP-1 and berberine can further support fat loss. These science-based tools go beyond traditional calorie counting to enhance metabolism and improve body composition.
Articles
- A role for brown adipose tissue in diet-induced thermogenesis (Nature)
- Accumulation of succinate controls activation of adipose tissue thermogenesis (Nature)
People Mentioned
- Christopher Gardner: professor, nutrition science, Stanford University

How to Lose Fat with Science-Based Tools
Huberman Lab Essentials are short episodes focused on essential science and protocol takeaways from past full-length Huberman Lab episodes.
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