Essentials
February 20, 2025

Essentials: How to Optimize Testosterone & Estrogen

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In this Huberman Lab Essentials episode, I explain how to optimize hormones—particularly testosterone, estrogen, and related sex steroids—to enhance fertility and overall well-being.

I discuss the sources of testosterone and estrogen and how their levels fluctuate with age in both males and females. I also cover how behaviors such as exercise, cold and heat exposure, light exposure, illness, and breathing patterns affect hormones. Additionally, I examine specific supplements and replacement therapies, highlighting important precautions to consider when adjusting hormone levels.

Huberman Lab Essentials episodes are approximately 30 minutes long and focus on key scientific insights and protocol takeaways from past Huberman Lab episodes. These short episodes will be released every Thursday, while our full-length episodes will continue to be released every Monday.

Resources

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  • 00:00:00 Huberman Lab Essentials; Hormones, Sexual Development
  • 00:01:15 Testosterone & Estrogen Sources & Age, Adrenals
  • 00:03:34 Competition, Males & Testosterone; Dopamine
  • 00:07:56 Testosterone Decreases, Expectant Fathers, Illness
  • 00:09:59 Sleep Apnea, Testosterone, Estrogen, Cortisol, Tool: Nasal Breathing
  • 00:14:25 Dopamine, Cortisol, Fertility, Tool: Light Viewing Behavior
  • 00:16:56 Heat, Cold & Hormone Levels
  • 00:18:39 Resistance & Endurance Training, Testosterone, Tool: Exercise Order
  • 00:20:51 Estrogen, Menopause, Hormone Therapy
  • 00:22:31 Vitamins, Opioids, Supplements, Tongkat Ali, Cancer Risk
  • 00:27:02 Luteinizing Hormone, hCG, Fadogia Agrestis, Tool: Blood Tests
  • 00:31:37 Recap & Key Takeaways

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